Foye's Principles of Medicinal Chemistry
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Foye's Principles of Medicinal Chemistry |
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基本信息·出版社：Lippincott Williams & Wilkins
·页码：1114 页
·出版日期：2002年02月
·ISBN：0683307371
·International Standard Book Number：0683307371
·条形码：9780683307375
·EAN：9780683307375
·版本：Fifth Edition
·装帧：精装
·正文语种：英语
内容简介 Massachusetts College of Pharmacy and Health Sciences, Boston. Textbook, for pharmacy students, now includes an overview of the drug development process from the perspective of an industrial research scientist. Also new to this edition: an overview of drug receptors, case studies, selected readings, and a companion web page. Previous edition: c1995.
目录 Preface Introduction: Origins of Medicinal Chemistry Part I: Principles of Drug Discovery Overview - Drug Design and Development: A Perspective 1. Natural Products 2. Drug Design and Relationship of Functional Groups to Pharmacologic Activity 3. Molecular Modeling and Drug Design 4. Receptors and Drug Action 5. Drug Design Through Enzyme Inhibition 6. Peptide and Protein Drugs 7. Physicochemical and Biopharmaceutical Properties of Drug Substances and Pharmacokinetics 8. Drug Metabolism 9. U.S. Drug Regulation: An Overview Part II: Pharmacodynamic Agents Overview - Drug Receptors: A Perspective Section 1 Drugs Affecting Neurotransmission 10. Drugs Affecting Cholinergic Neurotransmission 11. Drugs Affecting Adrenergic Neurotransmission 12. Serotonin Receptors and Drugs Affecting Serotonergic Neurotransmission 13. Local Anesthetics Section 2 Drugs Affecting Central Nervous System 14. Volatile Anesthetics 15. Hypnotics 16. Antiseizure Drugs 17. Psychotherapeutic Drugs: Antipsychotic and Anxiolytic Agents 18. Hallucinogens, Stimulants, and Related Drugs of Abuse 19. Opioid Analgesics 20. Drugs Used to Treat Neuromuscular Disorders: Antiparkinsonian and Spasmolytic Agents 21. Cardiac Agents: Cardiac Glycosides, Antianginal, and Antiarrhythmic Drugs 22. Diuretics 23. Angiotensin Antagonists and Calcium Blockers 24. Central and Peripheral Sympatholytics and Vasodilators 25. Antihyperlipoproteinemics and Inhibitors of Cholesterol Biosynthesis 26. Antithrombotics, Thrombolytics, Coagulants and Plasma Extenders Section 3 Drugs Affecting the Hormonal Systems 27. Insulin and Oral Hypoglycemic Drugs 28. Adrenocorticoids 29. Estrogen, Progestins and Androgens 30. Thyroid Function and Thyroid Drugs 31. Calcium Homeostasis Section 4 Drugs Affecting the Immune Systems 32. Nonsteroidal Anti-Inflammatory Agents 33. Antihistamines and Related Antiallergic and Antiulcer Agents Section 5 Chemotherapeutic Agents 34. Antibiotics and Antimicrobial Agents 35. Antiparasitic Agents 36. Antifungal Drugs 37. Antimycobacterial Agents 38. Cancer and Cancer Chemotherapy 39. Antiviral Agents and Protease Inhibitors Part III: Recent Advances in Drug Discovery 40. Pharmaceutical Biotechnology 41. Gene Therapy 42. Antisense Therapeutic Agents 43. Selective Estrogen Receptor Modulators Appendices: pKa Values for Some Drugs and Miscellaneous Organic Acids and Bases pH Values for Tissue Fluid
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