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Cancer Immunotherapy: Immune Suppression and Tumor Growth |
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Cancer Immunotherapy: Immune Suppression and Tumor Growth |
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基本信息·出版社：Academic Press
·页码：428 页
·出版日期：2007年06月
·ISBN：0123725518
·条形码：9780123725516
·装帧：精装
·正文语种：英语
内容简介 在线阅读本书
There has been major growth in understanding immune suppression mechanisms and its relationship to cancer progression and therapy. This book highlights emerging new principles of immune suppression that drive cancer and it offers radically new ideas about how therapy can be improved by attacking these principles. Following work that firmly establishes immune escape as an essential trait of cancer, recent studies have now defined specific mechanisms of tumoral immune suppression. It also demonstrates how attacking tumors with molecular targeted therapeutics or traditional chemotherapeutic drugs can produce potent anti-tumor effects in preclinical models. This book provides basic, translational, and clinical cancer researchers an indispensable overview of immune escape as a critical trait in cancer and how applying specific combinations of immunotherapy and chemotherapy to attack this trait may radically improve the treatment of advanced disease.
* Offers a synthesis of concepts that are useful to cancer immunologists and pharmacologists, who tend to work in disparate fields with little cross-communication
* Drs Prendergast and Jaffee are internationally recognized leaders in cancer biology and immunology who have created a unique synthesis of fundamental and applied concepts in this important new area of cancer research
* Summarizes the latest insights into how immune escape defines an essential trait of cancer
* Includes numerous illustrations including: how molecular-targeted therapeutic drugs or traditional chemotherapy can be combined with immunotherapy to improve anti-tumor efficacy; and how reversing immune suppression by the tumor can cause tumor regression
作者简介 Claude Oestges received a PhD degree in Applied Science from the Université catholique de Louvain (UCL, Belgium), in 2000. In 2001, he joined the Smart Antennas Research Group at Stanford University (California, USA) as a post-doctoral scholar. Since 2005 he has been a Research Associate of the Belgian National Science Foundation and a part-time Associate Professor at UCL. His research interests cover wireless and satellite communications, with a specific focus on the propagation channel and its impact on system performance. Claude Oestges is the author or co-author of more than 60 papers in IEEE/IEE journals and conference proceedings. He was a member of the IEEE 802.11 Standardization Working Group on "Multiple antenna channel modeling". He received the IEE Marconi Premium Award in 2001 and the IEEE Vehicular Technology Society 2004 Neal Shepherd Award.
Bruno Clerckx received a PhD degree in Applied Science from the Université catholique de Louvain (UCL, Belgium) in 2005. From September 2000 to August 2006, he was with the Microwave Laboratory UCL, as a Research Assistant and a PhD student funded by the Belgian National Science Foundation for Industrial Research, and as a Post-Doctoral Scholar. He held several visiting research positions, at the Smart Antennas Research Group, Stanford University (CA, USA), and at the Mobile Communication Department of Eurecom Institute. Bruno Clerckx is currently with the Communication & Network Laboratory of Samsung Advanced Institute of Technology (SAIT) in Korea. He is the author or co-author of more than 25 research papers and communications. He received the IEEE Symposium on Communications and Vehicular Technology Best Student Paper Award in 2002.
编辑推荐 Review
This relatively compact book is a summary of contemporary thinking about cancer immunotherapy, with a focus on the relationship between tumors and the immune response of the host. The book is edited by authorities on tumor biology and cancer immunotherapy and reflects the nascent synthesis of these disciplines. The chapters are written by highly respected investigators, and the topics span much of the breadth and depth of this evolving field. The book seems designed to provide an overview for those who wish to immerse themselves in this field and who have a working knowledge of immunotherapy but rudimentary familiarity with cancer immunobiology and therapy. - The New England Journal of Medicine, April 2008
Review
This relatively compact book is a summary of contemporary thinking about cancer immunotherapy, with a focus on the relationship between tumors and the immune response of the host. The book is edited by authorities on tumor biology and cancer immunotherapy and reflects the nascent synthesis of these disciplines. The chapters are written by highly respected investigators, and the topics span much of the breadth and depth of this evolving field. The book seems designed to provide an overview for those who wish to immerse themselves in this field and who have a working knowledge of immunotherapy but rudimentary familiarity with cancer immunobiology and therapy. - The New England Journal of Medicine, April 2008
